A synthetic peptide for use as a blocking control in assays to test for specificity of GDAP1 L1 antibody, Alternative Names: GDAP1L1 control peptide, GDAP1L1 antibody Blocking Peptide, Anti-GDAP1L1 Blocking Peptide, Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 Blocking Peptide, DKFZp761K228 Blocking Peptide, dJ881L22.1 Blocking Peptide, dJ995J12.1.1 Blocking Peptide
GDAP1L1
Reaktivität: Human, Ratte
Wirt: Synthetic
WB, BP
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
GDAP1L1
(Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1))
Synonyme
GDAP1L1 Peptide, MGC146673 Peptide, dJ881L22.1 Peptide, dJ995J12.1.1 Peptide, Gdap1l Peptide, ganglioside induced differentiation associated protein 1 like 1 Peptide, ganglioside induced differentiation associated protein 1-like 1 Peptide, ganglioside-induced differentiation-associated protein 1-like 1 Peptide, GDAP1L1 Peptide, gdap1l1 Peptide, Gdap1l1 Peptide
Hintergrund
The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. GDAP1L1 is similar in sequence to the human GDAP1 protein.