A synthetic peptide for use as a blocking control in assays to test for specificity of MLLT3 antibody, Alternative Names: MLLT3 control peptide, MLLT3 antibody Blocking Peptide, Anti-MLLT3 Blocking Peptide, myeloid/lymphoid or mixed-lineage leukemia, trithorax homolog, Drosophila, translocated to, 3 Blocking Peptide, AF9 Blocking Peptide, FLJ2035 Blocking Peptide, YEATS3 Blocking Peptide, MLLT3, MLLT-3, MLLT 3, MLLT-3 Blocking Peptide, MLLT 3 Blocking Peptide
Aufreinigung
The antibody is affinity purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice.