A synthetic peptide for use as a blocking control in assays to test for specificity of TOP2 B antibody, Alternative Names: TOP2B control peptide, TOP2B antibody Blocking Peptide, Anti-TOP2B Blocking Peptide, topoisomerase, DNA II beta 180kDa Blocking Peptide, TOPIIB Blocking Peptide, top2beta Blocking Peptide, TOP2B, TOPB-2, TOPB 2, TOPB-2 Blocking Peptide, TOPB 2 Blocking Peptide
TOP2B
Reaktivität: Human, Hund, Affe, Schwein
Wirt: Synthetic
BP
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
TOP2B
(Topoisomerase (DNA) II beta 180kDa (TOP2B))
Synonyme
TOP2B Peptide, D230016L12Rik Peptide, Top-2 Peptide, TOPIIB Peptide, top2beta Peptide, DNA topoisomerase II beta Peptide, topoisomerase (DNA) II beta Peptide, microRNA 4442 Peptide, TOP2B Peptide, Top2b Peptide, MIR4442 Peptide
Hintergrund
TOP2B is a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event.