A synthetic peptide for use as a blocking control in assays to test for specificity of HERC5 antibody, Alternative Names: HERC5 control peptide, HERC5 antibody Blocking Peptide, Anti-HERC5 Blocking Peptide, Hect Domain And Rld 5 Blocking Peptide, CEB1 Blocking Peptide, CEBP1 Blocking Peptide
HERC5
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
HERC5
(Hect Domain and RLD 5 (HERC5))
Synonyme
HERC5 Peptide, CEB1 Peptide, CEBP1 Peptide, HECT and RLD domain containing E3 ubiquitin protein ligase 5 Peptide, hect domain and RLD 5 Peptide, HERC5 Peptide
Hintergrund
This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.