A synthetic peptide for use as a blocking control in assays to test for specificity of ACAT1 antibody, Alternative Names: ACAT1 control peptide, ACAT1 antibody Blocking Peptide, Anti-ACAT1 Blocking Peptide, Acetyl-Coenzyme A Acetyltransferase 1 Blocking Peptide, ACAT Blocking Peptide, MAT Blocking Peptide, T2 Blocking Peptide, THIL Blocking Peptide, ACAT1, ACAT-1, ACAT 1, ACAT-1 Blocking Peptide, ACAT 1 Blocking Peptide
ACAT1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. The gene encoding ACAT1 spans approximately 27 kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.