A synthetic peptide for use as a blocking control in assays to test for specificity of SURF1 antibody, Alternative Names: SURF1 control peptide, SURF1 antibody Blocking Peptide, Anti-SURF1 Blocking Peptide, surfeit 1 Blocking Peptide, SURF1, SURF-1, SURF 1, SURF-1 Blocking Peptide, SURF 1 Blocking Peptide
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.