A synthetic peptide for use as a blocking control in assays to test for specificity of STAT5 B antibody, Alternative Names: STAT5B control peptide, STAT5B antibody Blocking Peptide, Anti-STAT5B Blocking Peptide, signal transducer and activator of transcription 5B Blocking Peptide, STAT5 Blocking Peptide, STAT5B, STATB-5, STATB 5, STATB-5 Blocking Peptide, STATB 5 Blocking Peptide
STAT5B
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
STAT5B
(Signal Transducer and Activator of Transcription 5B (STAT5B))
Synonyme
STAT5 Peptide, stat5 Peptide, STAT5A Peptide, STAT5B Peptide, signal transducer and activator of transcription 5B Peptide, signal transducer and activator of transcription 5B S homeolog Peptide, Signal transducer and activator of transcription 5B Peptide, STAT5B Peptide, Stat5b Peptide, stat5b.S Peptide, LOC490969 Peptide, sta5b Peptide, LOC100566752 Peptide, LOC100052954 Peptide
Hintergrund
STAT5B is a member of the STAT family of transcription factors. In response to cytokines andgrowth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression.