A synthetic peptide for use as a blocking control in assays to test for specificity of SNUPN antibody, Alternative Names: SNUPN control peptide, SNUPN antibody Blocking Peptide, Anti-SNUPN Blocking Peptide, Snurportin 1 Blocking Peptide, KPNBL Blocking Peptide, RNUT1 Blocking Peptide, Snurportin1 Blocking Peptide
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.