A synthetic peptide for use as a blocking control in assays to test for specificity of UNG antibody, Alternative Names: UNG control peptide, UNG antibody Blocking Peptide, Anti-UNG Blocking Peptide, uracil-DNA glycosylase Blocking Peptide, DGU Blocking Peptide, DKFZp781L1143 Blocking Peptide, HIGM4 Blocking Peptide, UDG Blocking Peptide, UNG1 Blocking Peptide, UNG15 Blocking Peptide, UNG2 Blocking Peptide
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene, which has been confused with this gene, in the literature and some databases.