A synthetic peptide for use as a blocking control in assays to test for specificity of GPHN antibody, Alternative Names: Gephyrin control peptide, Gephyrin antibody Blocking Peptide, Anti-Gephyrin Blocking Peptide, GPHN Blocking Peptide, GEPH Blocking Peptide, GPH Blocking Peptide, GPHRYN Blocking Peptide, KIAA1385 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
Gephyrin (GPHN)
Hintergrund
GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.