A synthetic peptide for use as a blocking control in assays to test for specificity of FGD1 antibody, Alternative Names: FGD1 control peptide, FGD1 antibody Blocking Peptide, Anti-FGD1 Blocking Peptide, FYVE, RhoGEF and PH domain containing 1, faciogenital dysplasia Blocking Peptide, AAS Blocking Peptide, FGDY Blocking Peptide, ZFYVE3 Blocking Peptide, FGD1, FGD-1, FGD 1, FGD-1 Blocking Peptide, FGD 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
FGD1
(FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
Hintergrund
FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs.