A synthetic peptide for use as a blocking control in assays to test for specificity of RFC3 antibody, Alternative Names: RFC3 control peptide, RFC3 antibody Blocking Peptide, Anti-RFC3 Blocking Peptide, Replication Factor C3 Blocking Peptide, MGC5276 Blocking Peptide, RFC38 Blocking Peptide, RFC3, RFC-3, RFC 3, RFC-3 Blocking Peptide, RFC 3 Blocking Peptide
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. RFC3 is the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits.