A synthetic peptide for use as a blocking control in assays to test for specificity of PMS2 antibody, Alternative Names: PMS2 control peptide, PMS2 antibody Blocking Peptide, Anti-PMS2 Blocking Peptide, Pms2 Postmeiotic Segregation Increased 2 Blocking Peptide, HNPCC4 Blocking Peptide, PMS2CL Blocking Peptide, PMSL2 Blocking Peptide, PMS2, PMS-2, PMS 2, PMS-2 Blocking Peptide, PMS 2 Blocking Peptide
PMS2
Reaktivität: Human
Wirt: Synthetic
BP, WB, ICo, IDe
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
PMS2
(PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
Hintergrund
PMS2 is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors.