A synthetic peptide for use as a blocking control in assays to test for specificity of MARCKS antibody, Alternative Names: MARCKS control peptide, MARCKS antibody Blocking Peptide, Anti-MARCKS Blocking Peptide, myristoylated alanine-rich protein kinase C substrate Blocking Peptide, 80K-L Blocking Peptide, FLJ14368 Blocking Peptide, FLJ90045 Blocking Peptide, MACS Blocking Peptide, PKCSL Blocking Peptide, PRKCSL Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
MARCKS
(Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
Hintergrund
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.