A synthetic peptide for use as a blocking control in assays to test for specificity of Psenen antibody, Alternative Names: Psenen control peptide, Psenen antibody Blocking Peptide, Anti-Psenen Blocking Peptide, presenilin enhancer 2 homolog, C. elegans Blocking Peptide, 1700023M09Rik Blocking Peptide, MGC102026 Blocking Peptide
Psenen is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.