A synthetic peptide for use as a blocking control in assays to test for specificity of ALG11 antibody, Alternative Names: ALG11 control peptide, ALG11 antibody Blocking Peptide, Anti-ALG11 Blocking Peptide, Asparagine-Linked Glycosylation 11 Homolog Blocking Peptide, GT8 Blocking Peptide, KIAA0266 Blocking Peptide
ALG11 is a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP).