A synthetic peptide for use as a blocking control in assays to test for specificity of HTRA4 antibody, Alternative Names: HTRA4 control peptide, HTRA4 antibody Blocking Peptide, Anti-HTRA4 Blocking Peptide, Htra Serine Peptidase 4 Blocking Peptide, FLJ90724 Blocking Peptide
HTRA4 is a member of the HtrA family of proteases. The protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.