A synthetic peptide for use as a blocking control in assays to test for specificity of OSMR antibody, Alternative Names: OSMR control peptide, OSMR antibody Blocking Peptide, Anti-OSMR Blocking Peptide, Oncostatin M Receptor Blocking Peptide, MGC150626 Blocking Peptide, MGC150627 Blocking Peptide, MGC75127 Blocking Peptide, OSMRB Blocking Peptide
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells.