This is a synthetic peptide designed for use in combination with anti-ADRBK1 Antibody(ARP51966_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Alias Symbols: BARK1, BETA-ARK1, FLJ16718, GRK2
Protein Interaction Partner: PEBP1,ADRA2A,AGTR1,AKAP12,ARRB1,BDKRB2,CAPN2,CAV1,CCR4,CCR5,EGF,EGFR,FPR1,FSHR,GIT1,GIT2,GNAQ,GRM1,MAPK3,MC4R,MDM2,NCS1,OPRD1,PDC,PDCL,PDE6G,PEBP1,PIK3CG,PRKACA,PRKCA,PRKCB,PRKCD,PRKCG,RCVRN,RHO,RPLP2,SNCA,SRC,TPM2,ADRB2,AGTR1,CAV1,CCR4,EDNRB,FSHR,GIT1,GI