This is a synthetic peptide designed for use in combination with anti-BAD antibody (Catalog #: ARP30325_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
BAD
Reaktivität: Human, Maus, Ratte, Rind (Kuh)
Wirt: Synthetic
BP
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
BAD
(BCL2-Associated Agonist of Cell Death (BAD))
Synonyme
bad Peptide, fa01b12 Peptide, wu:fa01b12 Peptide, wu:fa96d04 Peptide, BAD Peptide, BBC2 Peptide, BCL2L8 Peptide, AI325008 Peptide, Bbc2 Peptide, BCL2-associated agonist of cell death b Peptide, BCL2 associated agonist of cell death Peptide, BCL2-associated agonist of cell death Peptide, badb Peptide, BAD Peptide, Bad Peptide
Hintergrund
BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Alias Symbols: BBC2, BCL2L8
Protein Interaction Partner: BCL2,BCL2,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,AKT1,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L2,EWSR1,HRK,MAP2K5,MAPK8,MCL1,PAK1,PAK7,PIM1,PIM2,PIM3,PPP1CA,PPP3CA,PRKACA,RAF1,RPS6KA1,RPS6KA2,RPS6KA3,RPS6KA5,S100A10,SFN,SNCA,WASF1,YWHAB,YWHAE,YWHAG,YWHAH,YWHAQ,YWHAZ,AKT1,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,EWSR1,MCL1,PIM2,PRKACA,PRKCI,RPS6KA1,RPS6KA5,S100A10,SFN,SNCA,YWHAB,YWHAE,YWHAH,YWHAQ,YWHAZ