This is a synthetic peptide designed for use in combination with anti-BAG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Alias Symbols: HAP, RAP46
Protein Interaction Partner: HSPA4,AR,BCL2,BCL2L1,ESR1,HBEGF,HSPA1A,HSPA1B,HSPA8,MET,NR3C1,PDGFRB,PPP1R15A,PSMD1,RAF1,RARA,RB1,SIAH1,STUB1,VDR,AR,BCL2,ESR1,HBEGF,HSPA1A,HSPA4,HSPA8,MAPT,NR3C1,PPP1R15A,RAF1,RARA,RB1,SIAH1,STUB1,TP53,UBC,VDR