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B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (C-Term) Peptid

BCL11A Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN973776
  • Target Alle BCL11A Produkte
    BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    YACAQSSKLT RHMKTHGQVG KDVYKCEICK MPFSVYSTLE KHMKKWHSDR
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-BCL11A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
    Synonyme
    2810047E18Rik Peptide, BCL-11A Peptide, Ctip1 Peptide, D930021L15Rik Peptide, Evi9 Peptide, Evi9a Peptide, Evi9b Peptide, Evi9c Peptide, mKIAA1809 Peptide, BCL11A-L Peptide, BCL11A-S Peptide, BCL11A-XL Peptide, BCL11a-M Peptide, CTIP1 Peptide, EVI9 Peptide, HBFQTL5 Peptide, ZNF856 Peptide, bcl11a Peptide, wu:fi09f10 Peptide, zgc:136898 Peptide, B cell CLL/lymphoma 11A (zinc finger protein) Peptide, B-cell CLL/lymphoma 11A Peptide, B-cell CLL/lymphoma 11A L homeolog Peptide, B-cell CLL/lymphoma 11Aa Peptide, Bcl11a Peptide, BCL11A Peptide, bcl11a.L Peptide, bcl11aa Peptide
    Hintergrund
    BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.

    Alias Symbols: BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856

    Protein Interaction Partner: NR2F1,NR2F2,CHD4,HDAC1,MBD3,MTA1,MTA2,NR2F1,SIRT1

    Protein Size: 835
    Molekulargewicht
    91 kDa
    Gen-ID
    53335
    NCBI Accession
    NM_022893, NP_075044
    UniProt
    Q9H165
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