This is a synthetic peptide designed for use in combination with anti-BCL2 Antibody(ARP58872_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Alias Symbols: Bcl-2, PPP1R50
Protein Interaction Partner: BAD,BAD,BAX,BBC3,BCL2L11,BID,BIK,BIK,BMF,BNIPL,HRK,HRK,RHEB,MOAP1,ATP2A2,BAD,BAG1,BAG3,BAG4,BAK1,BAX,BBC3,BCAP31,BCL2,BCL2L1,BCL2L10,BCL2L11,BCL2L14,BCLAF1,BECN1,BFAR,BID,BIK,BLK,BMF,BNIP1,BNIP2,BNIP3,BNIP3L,BNIPL,CASP3,CASP8,CDK2,CPT1A,CYCS,FKBP8,HRAS,HR