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Calreticulin (CALR) Peptid

CALR Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN974409
  • Target Alle Calreticulin (CALR) Produkte
    Calreticulin (CALR)
    Spezies
    Human
    Quelle
    • 9
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CALR antibody (Catalog #: ARP30114_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Calreticulin (CALR)
    Synonyme
    CRT Peptide, RO Peptide, SSA Peptide, cC1qR Peptide, crc Peptide, crt Peptide, Calregulin Peptide, CG9429 Peptide, Clr Peptide, Dmel\\CG9429 Peptide, anon-EST:Liang-2.11 Peptide, anon-EST:Liang-2.17 Peptide, anon-EST:fe3D7 Peptide, clone 2.11 Peptide, clone 2.17 Peptide, eth Peptide, potp Peptide, cc1qr Peptide, ssa Peptide, NV19007 Peptide, CRP55 Peptide, ERp60 Peptide, HACBP Peptide, CHOT1 Peptide, CHT1 Peptide, CT1 Peptide, AA589632 Peptide, CRTR Peptide, Creat Peptide, CCDS1 Peptide, calrl2 Peptide, fc66d10 Peptide, wu:fc66d10 Peptide, wu:fj50c03 Peptide, zgc:66153 Peptide, calreticulin Peptide, calreticulin L homeolog Peptide, Calreticulin Peptide, putative calreticulin Peptide, solute carrier family 6 member 8 Peptide, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Peptide, CALR Peptide, calr.L Peptide, Crt Peptide, crt Peptide, CRT Peptide, Calr Peptide, calr Peptide, LMJF_31_2600 Peptide, Crc Peptide, Slc6a8 Peptide, SLC6A8 Peptide, LOC8269812 Peptide
    Hintergrund
    Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.

    Alias Symbols: RO, CRT, SSA, cC1qR

    Protein Interaction Partner: CALR,HLA-A,PDIA3,TSHR,APOB,APP,AR,B2M,CALR,CD1D,F5,F8,FBN1,FGB,HLA-C,ITGA2B,ITGA3,ITGAV,LPL,LRP1,MBL2,MTNR1A,NKX2-1,NR3C1,PDIA2,PDIA3,PLAT,PLP1,PRF1,SCARF1,SLC2A1,SLC6A4,SUMO4,TAPBP,TF,THBS1,TSHR,VWF,APOB,APP,AR,CANX,CD1D,CD40,ELF3,EPB41,F5,FGB,LRP1,MBL2,NKX2-1,NR3C1,PDIA3,PLAT,PRF1,SLC2A1,SLC6A4,TAPBP,TF,VWF

    Protein Size: 417
    Molekulargewicht
    48 kDa
    Gen-ID
    811
    NCBI Accession
    NM_004343, NP_004334
    UniProt
    P27797
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