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Chemokine (C-C Motif) Receptor 2 (CCR2) (C-Term) Peptid

CCR2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN974623
  • Target Alle CCR2 Produkte
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    FTIMIVYFLF WTPYNIVILL NTFQEFFGLS NCESTSQLDQ ATQVTETLGM
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CCR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    Hintergrund
    This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase.

    Alias Symbols: CKR2, CCR-2, CCR2A, CCR2B, CD192, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2

    Protein Size: 374
    Molekulargewicht
    42 kDa
    Gen-ID
    1231
    NCBI Accession
    NM_000647, NP_000638
    UniProt
    P41597
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