ECSIT Homolog (ECSIT) (N-Term) Peptid
ECSIT
Reaktivität: Maus
Wirt: Synthetic
BP, WB
-
- Target
- ECSIT (ECSIT Homolog (ECSIT))
- Protein Region
- N-Term
- Spezies
- Maus
- Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- EPWLVPRPPE PQRKPIKVPA MHEDSFKPSG NRERDKASFL NAVRSFGAHN
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Ecsit Antibody(ARP37175_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- ECSIT (ECSIT Homolog (ECSIT))
- Synonyme
- Sitpec Peptide, ECSIT signalling integrator Peptide, Ecsit Peptide
- Hintergrund
-
Ecsit is required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase. Ecsit is an adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1.Ecsit promotes proteolytic activation of MAP3K1. Ecsit is involved in the BMP signaling pathway. Ecsit is required for normal embryonic development.
Alias Symbols: Sitpec
Protein Interaction Partner: Irak1,Map3k1,SMURF1,TRAF6,Traf6
Protein Size: 435 - Molekulargewicht
- 50 kDa
- Gen-ID
- 26940
- NCBI Accession
- NM_012029, NP_036159
- UniProt
- Q9QZH6
-
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