Prothrombin (F2)
(Coagulation Factor II (thrombin) (F2))
Protein Region
Middle Region
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-F2 antibody (Catalog #: ARP41757_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PT
Protein Interaction Partner: F2R,AANAT,AKR7A2,AMBP,C6,CPB2,F11,F13A1,F2,F2R,F2RL1,F2RL2,F2RL3,F5,F8,F9,FGA,GGCX,GP1BA,GP5,HGFAC,IGFBP3,IGFBP5,ITGA2B,KNG1,PLAU,PROC,PROS1,PROZ,SERPINA5,SERPINB6,SERPINB8,SERPINC1,SERPIND1,SERPINE1,SERPINE2,SERPING1,SPP1,ST13,THBD,THBS1,CPB2,F5,FGA,ITGA2B,PLAT,SERPINB6,SERPIND1,SERPINE1,SERPING1,THBD,THBS1