This is a synthetic peptide designed for use in combination with anti-FRS3 antibody (Catalog #: ARP52228_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FRS2B, FRS2beta, MGC17167, SNT-2, SNT2
Protein Interaction Partner: FGFR1,NTRK1,PRKCI,BMPR2,FGFR1,GRB2,KARS,MAPK1,NTRK1,NTRK2,PRKCI,PTPN11,RND1,BMPR2,FGFR1