This is a synthetic peptide designed for use in combination with anti-HMGB1 antibody (Catalog #: ARP38109_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
HMGB1
(High Mobility Group Box 1 (HMGB1))
Synonyme
HMG1 Peptide, HMG3 Peptide, SBP-1 Peptide, DEF Peptide, HMG-1 Peptide, Hmg1 Peptide, amphoterin Peptide, p30 Peptide, hmgb1 Peptide, ik:tdsubc_1a5 Peptide, wu:fb23c02 Peptide, xx:tdsubc_1a5 Peptide, zgc:56110 Peptide, zgc:77104 Peptide, hmg-1 Peptide, hmg3 Peptide, sbp-1 Peptide, hmg1 Peptide, HMGB1 Peptide, Ac2-008 Peptide, high mobility group box 1 Peptide, high-mobility group box 1 Peptide, high mobility group box 1a Peptide, high mobility group box 1 L homeolog Peptide, high mobility group protein B1 Peptide, HMGB1 Peptide, Hmgb1 Peptide, hmgb1 Peptide, hmgb1a Peptide, hmgb1.L Peptide, LOC100359149 Peptide
Hintergrund
HMGB1 belongs to the HMGB family. It contains 2 HMG box DNA-binding domains. The protein binds preferentially single-stranded DNA and unwinds double stranded DNA. The oxidized HMGB1 may accumulate even in cells under oxidative stress.
Alias Symbols: DKFZp686A04236, HMG1, HMG3, SBP-1
Protein Interaction Partner: HNRNPK,MECP2,RB1,TP53,TP73,TP73,AES,AGER,AR,ATOH1,C14orf1,C1orf103,CASP3,CEBPB,CRMP1,CSNK1A1,CTCF,CUX1,DNMT1,ERF,FOXA3,FOXC1,HES1,HNRNPK,HOXD9,HR,IRF2,MECP2,MNT,NCAN,NEUROD6,NFKB1,PLAT,PLG,POU5F1,PPP2R3A,PRKCA,PRKDC,RAG1,RASSF4,RB1,RBPJ,RELA,RFX1,SIX5,SOX18,TAF1,TBP,TFE3,TGIF1,TLE1,TLE2,TLR2,TLR4,TP53,TP73,UNC119,ZFP36,AES,AR,C14orf1,C1orf103,CDK1,CRMP1,CSNK1A1,GTF2A1,HNRNPK,HOXB1,HOXB3,HOXC6,HOXD10,HOXD11,HOXD3,HOXD8,HOXD9,MECP2,NCAN,NFKB1,NR3C1,PGR,PLAT,PLG,POU5F1,PTPRZ1,RAG1,RB1,RELA,TBP,TLE1,TP53,TP73,UBC,UNC119