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Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL) (C-Term) Peptid

HNRPDL Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978108

Kurzübersicht für Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL) (C-Term) Peptid (ABIN978108)

Target

HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

Spezies

Human

Quelle

  • 9
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-HNRPDL antibody (Catalog #: ARP40586_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

    Hintergrund

    HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPDL has two RRM domains that bind to RNAs. Two alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein is similar to its family member HNRPD.

    Alias Symbols: HNRNP, JKTBP, JKTBP2, laAUF1, HNRPDL

    Protein Interaction Partner: ATIC,HGS,HNRNPA1,KHDRBS2

    Protein Size: 420

    Molekulargewicht

    46 kDa

    Gen-ID

    9987

    NCBI Accession

    NM_005463, NP_005454

    UniProt

    O14979
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