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Islet Amyloid Polypeptide (IAPP) (N-Term) Peptid

IAPP Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN978369
  • Target Alle Amylin/DAP (IAPP) Produkte
    Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 23
    Synthetic
    Applikation
    Western Blotting (WB), Blocking Peptide (BP)
    Sequenz
    MGILKLQVFL IVLSVALNHL KATPIESHQV EKRKCNTATC ATQRLANFLV
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-IAPP Antibody(ARP41728_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
    Synonyme
    DAP Peptide, IAP Peptide, LOC100230121 Peptide, Amylin Peptide, islet amyloid polypeptide Peptide, IAPP Peptide, Iapp Peptide
    Hintergrund
    Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

    Alias Symbols: AMYLIN, DAP, IAP

    Protein Interaction Partner: COL25A1,PCSK1,PCSK2,PDX1,RAMP1,RAMP2

    Protein Size: 89
    Molekulargewicht
    4 kDa
    Gen-ID
    3375
    NCBI Accession
    NM_000415, NP_000406
    UniProt
    P10997
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