This is a synthetic peptide designed for use in combination with anti-IL2RB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Alias Symbols: CD122, P70-75, IL15RB
Protein Interaction Partner: GNB2L1,IL2,JAK1,CISH,EIF3B,FYN,GNB2L1,GRB2,IL15,IL15RA,IL2,IL2RA,IL2RG,JAK1,JAK3,LCK,LYN,PIK3R1,PTPN6,RAF1,SHB,SHC1,SOCS1,SOCS3,STAT1,STAT3,STAT5A,STAT5B,SYK,CISH,GNB2L1,GRB2,HGS,JAK1,JAK2,SHB,SHC1,SOCS1,STAT1,STAT3,STAT5A,STAT5B,UBC