This is a synthetic peptide designed for use in combination with anti-Lmx1a Antibody(ARP37428_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Lmx1a acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Lmx1a is required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.
Alias Symbols: Lmx1.1, MGC129356, MGC129357, dr, dreher, sst