This is a synthetic peptide designed for use in combination with anti-NGFR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Alias Symbols: CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR
Protein Interaction Partner: LINGO1,NGF,NGF,NTF4,RTN4R,RTN4R,RTN4R,SORT1,TRADD,BEX1,CAV1,FSCN1,GRB2,IL2,KIDINS220,LINGO1,MAG,MAGED1,MAGEH1,MAPK1,MAPK3,NDN,NFKBIB,NGF,NGFRAP1,NTF4,NTRK1,NTRK2,NTRK3,PRKACB,PTPN13,RIPK2,RTN4R,SHC1,SORT1,TRA2B,TRADD,TRAF2,TRAF4,TRAF6,ZNF274,CAV1,FSCN1,MAGED1,MAGEH1,MYCN,NDN,NDNL2,NGF,NGFRAP1,PIAS2,PRKACB,SHC1,SP1,TCF19,TRADD,TRAF1,TRAF2,TRAF3,TRAF4,TRAF5,TRAF6,TRIM37