NOP2/Sun Domain Family, Member 2 (NSUN2) Peptid
NSUN2
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle NSUN2 Produkte
- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NSUN2 antibody (Catalog #: ARP48811_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
- Synonyme
- D13Wsu123e Peptide, Misu Peptide, MISU Peptide, MRT5 Peptide, SAKI Peptide, TRM4 Peptide, RGD1311954 Peptide, NOL1/NOP2/Sun domain family member 2 Peptide, NOP2/Sun RNA methyltransferase family member 2 Peptide, NOP2/Sun RNA methyltransferase family, member 2 Peptide, NOP2/Sun RNA methyltransferase family member 2 S homeolog Peptide, Nsun2 Peptide, NSUN2 Peptide, nsun2.S Peptide
- Hintergrund
-
Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 is a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA).Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA) (Brzezicha et al., 2006 [PubMed 17071714]).[supplied by OMIM].
Alias Symbols: FLJ20303, MISU, SAKI, TRM4
Protein Interaction Partner: AURKB,PMS2
Protein Size: 767 - Molekulargewicht
- 86 kDa
- Gen-ID
- 54888
- NCBI Accession
- NM_017755, NP_060225
- UniProt
- Q08J23
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