Paired Box 3 (PAX3) Peptid
PAX3
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle Paired Box 3 (PAX3) Produkte
- Paired Box 3 (PAX3)
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PAX3 antibody (Catalog #: ARP32736_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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Paired Box 3 (PAX3) peptide
PAX3 Reaktivität: Human, Maus, Ratte, Rind (Kuh) Wirt: Synthetic BP, Imm
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Paired Box 3 (PAX3)
- Synonyme
- PAX3 Peptide, cdhs Peptide, hup2 Peptide, pax-3 Peptide, ws1 Peptide, xpax3 Peptide, Pax3 Peptide, pax3 Peptide, pax3b Peptide, xPax3-B Peptide, CDHS Peptide, HUP2 Peptide, WS1 Peptide, WS3 Peptide, Pax-3 Peptide, Sp Peptide, splotch Peptide, zgc:92547 Peptide, paired box 3 Peptide, paired box 3 L homeolog Peptide, paired box 3a Peptide, PAX3 Peptide, pax3 Peptide, pax3.L Peptide, Pax3 Peptide, pax3a Peptide
- Hintergrund
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PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Alias Symbols: WS1, WS3, CDHS, HUP2
Protein Interaction Partner: CIB1,DAXX,MEOX1,MEOX2,MITF,MSX1,PAX3,SOX10,SOX8,WWTR1,CNR1,DAXX,IPO13,IPO13,MEOX1,MEOX2,MSX1,POU3F2,PSMD4,RAD23B,Rad23b,SOX10,SOX10,TBP,UBC,Ubc
Protein Size: 479 - Molekulargewicht
- 53 kDa
- Gen-ID
- 5077
- NCBI Accession
- NM_181457, NP_852122
- UniProt
- P23760
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