This is a synthetic peptide designed for use in combination with anti-PAX6 antibody (Catalog #: ARP32741_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
PAX6 is one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA,This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.
Alias Symbols: AN, AN2, D11S812E, MGC17209, MGDA, WAGR
Protein Interaction Partner: HOXB1,IPO13,PBX1,CDX2,DIAPH1,DLG1,DYNLL1,EN1,EP300,HIPK2,HOMER3,HOXB1,INADL,IPO13,MAFG,MITF,PBX1,RAX,RGS3,SHANK3,SIX3,SMARCA4,SOX10,SOX3,TBP,TRIM11,VSX2,CDX2,EN1,EP300,HOXB1,IPO13,LHX2,MITF,PAX6,PKNOX1,PROX1,RAX,RB1,SIX3,SOX2,TAF1,TBP,VSX2