This is a synthetic peptide designed for use in combination with anti-PHB2 antibody (Catalog #: ARP48316_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
Alias Symbols: BAP, BCAP37, Bap37, MGC117268, PNAS-141, REA, p22
Protein Interaction Partner: ESR1,PTMA,AKT1,ESR1,HDAC1,HDAC2,HDAC3,HDAC5,MEF2A,MYOD1,PTMA,UPF2,CDC25B,COPG,CTNNB1,DDX20,EPPK1,ESR1,JUP,LGALS3BP,MMS19,NUP205,NUP93,PDXDC1,PTMA,RIPK2,RUNX3,SERINC3,SIRT2,TFE3,TH1L,TIMM50,USP15