This is a synthetic peptide designed for use in combination with anti-PHLDA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
PHLDA2
(Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))
Synonyme
PHLDA2 Peptide, ipl Peptide, phlda2 Peptide, BRW1C Peptide, BWR1C Peptide, HLDA2 Peptide, IPL Peptide, TSSC3 Peptide, Ipl Peptide, Tssc3 Peptide, zgc:110459 Peptide, pleckstrin homology like domain family A member 2 Peptide, Pleckstrin homology-like domain family A member 2 Peptide, pleckstrin homology like domain, family A, member 2 Peptide, pleckstrin homology-like domain, family A, member 2 Peptide, pleckstrin homology-like domain, family A, member 2 L homeolog Peptide, PHLDA2 Peptide, phla2 Peptide, Phlda2 Peptide, phlda2.L Peptide, phlda2 Peptide
Hintergrund
This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene regulates placental growth.