Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptid
PYHIN1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle PYHIN1 Produkte
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PYHIN1 antibody (Catalog #: ARP50876_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- Synonyme
- IFIX Peptide, RP11-520H16.1 Peptide, 4930422C14 Peptide, AI447904 Peptide, Ifi209 Peptide, Ifix Peptide, pyrin and HIN domain family member 1 Peptide, interferon activated gene 209 Peptide, PYHIN1 Peptide, Ifi209 Peptide
- Hintergrund
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PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Size: 452 - Molekulargewicht
- 51 kDa
- Gen-ID
- 149628
- NCBI Accession
- NM_198930, NP_945148
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