This is a synthetic peptide designed for use in combination with anti-RIPK1 antibody (Catalog #: AVARP02038_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex.
Alias Symbols: RIP, RIP1
Protein Interaction Partner: EhV2gp75,HHV8gp76,MC159L,PTK2,TNFAIP3,TRAF2,TRAF2,ZFAND5,CASP8,CFLAR,CRADD,EGFR,FADD,FAS,HSP90AA1,IKBKG,MAP3K14,MAP3K3,MAP3K8,NFKB1,PTK2,RIPK1,RIPK3,RNF216,SQSTM1,TICAM1,TNFAIP3,TNFRSF10A,TNFRSF10B,TNFRSF1A,TRADD,TRAF1,TRAF2,TRAF3,TRAF5,TRIM38,TRPC4AP,ZFAND5,BIRC2,BIRC3,CA11,CASP10,CASP8,CFLAR,CRADD,CYLD,EGFR,FADD,FAS,HSP90AA1,IKBKG,ITCH,MAP3K14,MAP3K7,RIPK3,RNF11,RNF216,SQSTM1,TAB2,TAX1BP1,TICAM1,TNFAIP3,TNFRSF10B,TNFRSF1A,TRADD,TRAF1,TRAF2,TRAF3,TRAF5,TRPC4AP,UBC