SMAD7
(SMAD, Mothers Against DPP Homolog 7 (SMAD7))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-SMAD7 antibody (Catalog #: ARP32008_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
SMAD7
Reaktivität: Human, Maus, Schwein, Ratte
Wirt: Synthetic
BP
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
SMAD7
(SMAD, Mothers Against DPP Homolog 7 (SMAD7))
Synonyme
CRCS3 Peptide, MADH7 Peptide, MADH8 Peptide, Smad7a Peptide, Madh7 Peptide, Smad10 Peptide, madh7 Peptide, xsmad7 Peptide, wu:fj60c10 Peptide, SMAD family member 7 Peptide, SMAD family member 7 L homeolog Peptide, SMAD7 Peptide, Smad7 Peptide, smad7.L Peptide, smad7 Peptide
Hintergrund
Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
Alias Symbols: CRCS3, MADH7, MADH8
Protein Interaction Partner: SMURF1,SMURF2,ACVR1B,AKT1,ASH1L,AXIN1,BMPR1B,CTNNB1,CXXC5,DVL1,EP300,ERBB2IP,HAT1,HEYL,KDM2A,MAP2K3,MAP2K6,MAP3K7,MAPK14,MBD1,MYOD1,PARD3,PIAS1,PIAS4,RNF111,SASH3,SMAD6,SMAD7,SMURF1,SMURF2,SOX13,SOX5,SOX7,STAMBP,STAMBPL1,STRAP,TAB1,TGFBR1,TGFBR2,TTF1,TTF2,XRCC6,YAP1,ZBTB11,ZBTB44,ZNF107,ACVR1B,AKT1,BMPR1A,CTNNB1,DVL1,EP300,ERBB2IP,LEF1,MAP2K3,MAP2K6,MAP3K7,MAPK14,PARD3B,PIAS4,RNF111,SMAD2,SMAD3,SMAD4,SMAD6,SMURF1,SMURF2,STAMBP,STRAP,TAB1,TGFBR1,TGFBR2,Wwp2,YAP1