Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-TARDBP antibody (Catalog #: ARP35837_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
TARDBP
Reaktivität: Human, Maus
Wirt: Synthetic
BP, BI
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
TARDBP
(TAR DNA Binding Protein (TARDBP))
Synonyme
TARDBP Peptide, TDP43 Peptide, DKFZp459I2127 Peptide, tardbp Peptide, ALS10 Peptide, TDP-43 Peptide, 1190002A23Rik Peptide, C85084 Peptide, Tdp43 Peptide, wu:fb77f02 Peptide, wu:fc52g10 Peptide, TAR DNA binding protein Peptide, Tardbp protein Peptide, TAR DNA binding protein L homeolog Peptide, TAR DNA-binding protein 43-like Peptide, TARDBP Peptide, tardbp Peptide, tardbp.L Peptide, Tardbp Peptide, LOC100621383 Peptide
Hintergrund
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TDP-43, ALS10
Protein Interaction Partner: EXOSC10,NSFL1C,SETDB1,XRN2,ZHX1,EXOSC10,HNRNPA1,KHDRBS2,NSFL1C,SETDB1,UBC,XRN2,ZHX1