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T-Box 19 (TBX19) Peptid

TBX19 Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN984831
  • Target Alle T-Box 19 (TBX19) Produkte
    T-Box 19 (TBX19)
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-TBX19 antibody (Catalog #: ARP32363_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    T-Box 19 (TBX19)
    Synonyme
    TBX19 Peptide, TBS19 Peptide, TPIT Peptide, dJ747L4.1 Peptide, CH-TBXT Peptide, TBXT Peptide, AU019250 Peptide, D1Ertd754e Peptide, Tpit Peptide, T-box 19 Peptide, TBX19 Peptide, Tbx19 Peptide
    Hintergrund
    TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX19 is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.

    Alias Symbols: TPIT, TBS19, dJ747L4.1

    Protein Interaction Partner: NR5A1

    Protein Size: 448
    Molekulargewicht
    48 kDa
    Gen-ID
    9095
    NCBI Accession
    NM_005149, NP_005140
    UniProt
    O60806
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