This is a synthetic peptide designed for use in combination with anti-TRIM23 antibody (Catalog #: ARP32672_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Alias Symbols: ARD1, ARFD1, RNF46
Protein Interaction Partner: C19orf57,CYTH1,CYTH2,FLAD1,GEM,GGA2,LNX1,POM121,RIBC2,SF1,TRIM23,TRIM27,TRIM29,TRIM31,ZNF250,ZNF581,C19orf57,CYTH1,CYTH2,FLAD1,GEM,GGA2,LNX1,POM121,RIBC2,SF1,TRIM23,TRIM27,TRIM28,TRIM29,TRIM31,TRIM32,TRIM6,ZNF250,ZNF581