This is a synthetic peptide designed for use in combination with anti-UBE2I antibody (Catalog #: ARP43021_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2I is a member of the E2 ubiquitin-conjugating enzyme family.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: C358B7.1, P18, UBC9
Protein Interaction Partner: CBX4,CEBPE,CHD3,DAXX,DNMT3B,E1,HIPK2,HTNVsSgp1,KCNK1,PIAS1,PIAS2,RANBP2,SALL1,SIAH1,SIAH1,SIAH2,SIAH2,SUMO1,SUMO1,TDP2,TP53,TP53,TRAF4,APEX1,AR,ARNT,ATF2,ATXN1,BLMH,C18orf25,CBX4,CEBPE,CHD3,CHMP1A,CHMP4B,DACH1,DAXX,DNMT3A,DNMT3B,ELK1,EP300,ESR1,ETS1,ETV6,FAS,FHIT,FMR1,GMEB1,GMEB2,HABP4,HDAC1,HGS,HIPK2,HIST2H4A,HNF4A,HNRNPD,HNRNPK,HSF2,IKZF1,IKZF3,IPO13,JUN,KCNK1,LMNA,MAPK1IP1L,MITF,MKL1,MYB,NIN,NR1D2,NR1H2,NR3C1,NUDCD3,PDLIM7,PHC1,PIAS1,PIAS2,PPM1J,PRPF40A,PTEN,RAD51,RAD52,RAD54B,RANBP2,RANGAP1,RIPK2,RORB,SALL1,SATB1,SCNN1A,SKIL,SLC2A1,SLC2A4,SMAD4,SNIP1,SOX10,SOX4,SP100,SP3,SREBF1,SREBF2,STAT1,STRA13,SUMO1,SUMO2,SUMO3,TCF3,TDP2,TFAP2B,TFAP2C,TNFRSF1A,TOP1,TOPORS,TP53,TRAF4,TRIM29,TRIM63,UBA2,UBE2I,UCHL1,UNC119,WT1,ZBED1,ZNF451,ZNF646,AR,ATF2,BLMH,C18orf25,CHD3,CHMP4B,CHUK,DACH1,DAXX,DNMT3A,DNMT3B,ESR1,ETS1,FAS,FHIT,FMR1,GCM1,HDAC4,HGS,HIPK2,HNRNPC,HNRNPK,HSF2,IKZF1,IKZF3,IPO13,JUN,MAP3K1,MAPK1IP1L,MITF,NUDCD3,PDLIM7,PDZK1,PHC1,PIAS1,PIAS2,PML,PPM1J,PTEN,RAD51,RAD52,RAD54B,RANBP2,RANBP2,RANGAP1,RANGAP1,RB1,RIPK2,Rangap1,SAE1,SALL1,SATB1,SCNN1A,SIAH1,SIAH2,SMAD4,SP100,SREBF1,SREBF2,SUMO1,SUMO3,SUZ12,Scnn1g,TCF3,TDG,TDP2,TNFRSF1A,TOP1,TOPORS,TP53,TP73,TRIM29,TRIM54,TRIM55,TRIM63,UBA2,UBE2I,UBE2K,UCHL1,UNC119,WT1,ZBED1,ZNF451,ZNF646