Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-ZIC2 antibody (Catalog #: ARP35821_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
ZIC2
Synonyme
HPE5 Peptide, Ku Peptide, cb851 Peptide, fb26a03 Peptide, wu:fb26a03 Peptide, zic2 Peptide, zic2.1 Peptide, hpe5 Peptide, hm:zeh0655 Peptide, id:ibd5017 Peptide, zic2.2 Peptide, zic2l Peptide, Zic family member 2 Peptide, zinc finger protein of the cerebellum 2 Peptide, zic family member 2 (odd-paired homolog, Drosophila), a Peptide, Zic family member 2 L homeolog Peptide, zic family member 2 (odd-paired homolog, Drosophila) b Peptide, ZIC2 Peptide, Zic2 Peptide, zic2a Peptide, zic2.L Peptide, zic2b Peptide
Hintergrund
ZIC2 is a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects.This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Alias Symbols: HPE5
Protein Interaction Partner: GLI1,GLI2,GLI3,GLI1,GLI2,GLI3,RNF180,UBC