PHD1 Produkte
(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
Kategorien
The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011].
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Ausgewählte PHD1 Kategorien
PHD1 Antikörper
High quality antibodies with extensive validation data.
PHD1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PHD1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7151444
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN652648
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (3)
Kat. Nr.
ABIN1679676
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PHD1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6216907
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PHD1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352447
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2720027
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136829
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PHD1 Produkten
: "Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells." in: Cancer letters, Vol. 390, pp. 11-20, (2017) (PubMed).: "Changes in Hypoxia-Inducible Factor-1 (HIF-1) and Regulatory Prolyl Hydroxylase (PHD) Enzymes Following Hypoxic-Ischemic Injury in the Neonatal Rat." in: Neurochemical research, Vol. 41, Issue 3, pp. 515-22, (2016) (PubMed).
: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." in: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
: "EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor." in: Oncotarget, Vol. 8, Issue 4, pp. 6787-6795, (2016) (PubMed).
: "PHD1 regulates p53-mediated colorectal cancer chemoresistance." in: EMBO molecular medicine, Vol. 7, Issue 10, pp. 1350-65, (2015) (PubMed).
: "Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27." in: Molecular cancer, Vol. 14, pp. 143, (2015) (PubMed).
: "EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer." in: The EMBO journal, Vol. 34, Issue 23, pp. 2953-70, (2015) (PubMed).
: "Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase." in: Genes & development, Vol. 28, Issue 13, pp. 1429-44, (2014) (PubMed).
: "Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells." in: PLoS pathogens, Vol. 10, Issue 9, pp. e1004400, (2014) (PubMed).
: "High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1α." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 1, pp. 206-17, (2014) (PubMed).
Synonyme und alternative Namen zu PHD1
egl-9 family hypoxia-inducible factor 1 (egln1), egl-9 family hypoxia inducible factor 2 (EGLN2), Egl nine homolog 2 (egln2), egl-9 family hypoxia-inducible factor 2 L homeolog (egln2.L), egl-9 family hypoxia-inducible factor 2 (Egln2), 0610011A13Rik, C85656, egln2, EIT6, Hif-p4h-1, HIF-PH1, HIFPH1, HPH-1, HPH-3, Ier4, PHD-1, PHD1, Phd1, phd2, SM-20Bezeichner auf Proteinebene für PHD1
- EGL nine homolog 2
- egl nine homolog 2
- Egl nine homolog 2
- EGL nine (C.elegans) homolog 2
- egl nine homolog 2 (C. elegans)
- egl nine homolog 2-like
- HIF-PH1
- HIF-prolyl hydroxylase 1
- HPH-1
- falkor
- hypoxia-inducible factor prolyl hydroxylase 1
- immediate early response 4
- prolyl hydroxylase domain-containing protein 1
- HIF-1alpha prolyl-4-hydroxylase-1
- estrogen-induced tag 6
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