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Phospholamban Produkte

(Phospholamban (PLN))
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008].

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Ausgewählte Phospholamban Kategorien

Phospholamban Antikörper

High quality antibodies with extensive validation data.

Phospholamban ELISA Kits

Reliable ELISA kits for a wide range of species.

Phospholamban Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Phospholamban Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7442687
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC, FACS
Validierungen
  • (5)
Kat. Nr. ABIN3032226
Menge 0.4 mL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validierungen
  • (2)
Kat. Nr. ABIN682468
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Phospholamban ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969290
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958555
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1571936
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Phospholamban Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1315443
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7412563
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7395149
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Phospholamban Produkten

Jin, Nesbitt, Yang, Chen, Horowitz, Jones, Vandergaast, Carey, Reiter, Russell, Kyratsous, Hooper, Hamilton, Ferreira, Deng, Straus, Baras, Hillyer, Luchsinger: "Seroprevalence of anti-SARS-CoV-2 antibodies in a cohort of New York City metro blood donors using multiple SARS-CoV-2 serological assays: Implications for controlling the epidemic and "Reopening"." in: PloS one, Vol. 16, Issue 4, pp. e0250319, (2021) (PubMed).

Stathopoulou, Schobesberger, Bork, Sprenger, Perera, Sotoud, Geertz, David, Christ, Nikolaev, Cuello: "Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes." in: Cellular signalling, Vol. 63, pp. 109362, (2019) (PubMed).

Kushnir, Santulli, Reiken, Coromilas, Godfrey, Brunjes, Colombo, Yuzefpolskaya, Sokol, Kitsis, Marks: "Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure." in: Circulation, Vol. 138, Issue 11, pp. 1144-1154, (2019) (PubMed).

Rigatti, Le, Gerber, Moraru, Dodge-Kafka: "Phosphorylation state-dependent interaction between AKAP7δ/γ and phospholamban increases phospholamban phosphorylation." in: Cellular signalling, Vol. 27, Issue 9, pp. 1807-15, (2015) (PubMed).

Kienesberger, Pulinilkunnil, Sung, Nagendran, Haemmerle, Kershaw, Young, Light, Oudit, Zechner, Dyck: "Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction." in: Molecular and cellular biology, Vol. 32, Issue 4, pp. 740-50, (2012) (PubMed).

Møller, Pham, Gustafsson, Hedley, Ersbøll, Bundgaard, Andersen, Torp-Pedersen, Køber, Christiansen: "The role of Lamin A/C mutations in Danish patients with idiopathic dilated cardiomyopathy." in: European journal of heart failure, Vol. 11, Issue 11, pp. 1031-5, (2009) (PubMed).

Prasad, Inesi: "Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes." in: American journal of physiology. Cell physiology, Vol. 296, Issue 5, pp. C992-C1002, (2009) (PubMed).

Pantos, Mourouzis, Markakis, Dimopoulos, Xinaris, Kokkinos, Panagiotou, Cokkinos: "Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 32, Issue 2, pp. 333-9, (2007) (PubMed).

Rodriguez, Kranias: "Phospholamban: a key determinant of cardiac function and dysfunction." in: Archives des maladies du coeur et des vaisseaux, Vol. 98, Issue 12, pp. 1239-43, (2006) (PubMed).

Kaliman, Catalucci, Lam, Kondo, Gutiérrez, Reddy, Palacín, Zorzano, Chien, Ruiz-Lozano: "Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8016-21, (2005) (PubMed).

Synonyme und alternative Namen zu Phospholamban

phospholamban (PLN), phospholamban (pln), phospholamban (Pln), cmd1p, CMD1P, CMH18, LOC100226261, plb, PLB, Plb, Plm

Bezeichner auf Proteinebene für Phospholamban

  • phospholamban
  • cardiac phospholamban
  • PLB
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