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PIAS2 Produkte

(Protein Inhibitor of Activated STAT, 2 (PIAS2))

Kategorien

This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011].

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Ausgewählte PIAS2 Kategorien

PIAS2 Antikörper

High quality antibodies with extensive validation data.

PIAS2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PIAS2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, PLA, RNAi
Validierungen
  • (5)
Kat. Nr. ABIN563927
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (4)
Kat. Nr. ABIN522502
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human, Monkey, Mouse, Rat
Applikation WB, ELISA, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6264196
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PIAS2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6206674
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PIAS2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124649
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314991
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1788102
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PIAS2 Produkten

Saito, Novak, Piovan, Basso, Sumazin, Schneider, Crespo, Shen, Bhagat, Califano, Chadburn, Pasqualucci, Dalla-Favera: "BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 27, pp. 11294-9, (2009) (PubMed).

Jones, Fusi, Higham, Abdel-Hafiz, Horwitz, Lam, Brosens: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).

van den Akker, Ano, Shih, Wang, Pironin, Palvimo, Kotaja, Kirsh, Dejean, Ghysdael: "FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family." in: The Journal of biological chemistry, Vol. 280, Issue 45, pp. 38035-46, (2005) (PubMed).

Sakurai, Itoh, Higashitsuji, Nagao, Nonoguchi, Chiba, Fujita: "A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells." in: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 15505-14, (2004) (PubMed).

Arora, Liu, He, Kim, Murphy, Murphy, Modlin, Shuai: "PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21327-30, (2003) (PubMed).

Wu, Cetinkaya, Munoz-Alonso, von der Lehr, Bahram, Beuger, Eilers, Leon, Larsson: "Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter." in: Oncogene, Vol. 22, Issue 3, pp. 351-60, (2003) (PubMed).

Liu, Liao, Rao, Kushner, Chung, Chang, Shuai: "Inhibition of Stat1-mediated gene activation by PIAS1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 18, pp. 10626-31, (1998) (PubMed).

Synonyme und alternative Namen zu PIAS2

protein inhibitor of activated STAT 2 L homeolog (pias2.L), protein inhibitor of activated STAT 2 (PIAS2), protein inhibitor of activated STAT, 2 (pias2), protein inhibitor of activated STAT 2 (Pias2), protein inhibitor of activated STAT, 2 (Pias2), 6330408K17Rik, AI462206, ARIP3, AU018068, Dib, DIP, MGC83751, MIZ, Miz1, MIZ1, PIAS2, piasx, PIASX, PIASX-ALPHA, PIASX-BETA, PIASxalpha, PIASxb, PIASxbeta, SIZ2, wu:fi05f09, ZMIZ4

Bezeichner auf Proteinebene für PIAS2

  • protein inhibitor of activated STAT, 2
  • protein inhibitor of activated STAT X
  • protein inhibitor of activated STAT2
  • E3 SUMO-protein ligase PIAS2
  • E3 SUMO-protein ligase PIAS2-like
  • e3 SUMO-protein ligase PIAS2-like
  • DAB2-interacting protein
  • DIP
  • Msx-interacting-zinc finger
  • PIASxalpha6
  • androgen receptor-interacting protein 3
  • msx-interacting zinc finger protein
  • protein inhibitor of activated STAT x
  • zinc finger, MIZ-type containing 4
  • ARIP3
  • msx-interacting-zinc finger protein
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